• Vorsitz / Chair: Simona Schlereth (Köln)
• Vorsitz / Chair: Friedemann Kiefer (Münster)

Inflammation is a rapid and highly effective response to a wide range of noxae ranging from injury and infection via sterile damage and environmental irritants to cancer. While tight control of this potentially damaging response results in full restitution of tissue function, derailed inflammation is a central component of most widespread diseases. Likewise, ocular inflammation is involved in dry eye disease, oGVDH, allergies, corneal transplant rejection, uveitis and the response against conjunctival melanoma. The need for research in this field is therefore still very high and has recently been met by an increase in research funding in ophthalmology. We highlight the collaborative research center CRC1607 „Towards immunomodulatory and anti(lymph)angiogenic therapies for age-related blinding eye diseases”, dedicated to advancing ophthalmology and preventing blindness.
A central determinate for the action of innate immune cells is (lymph)-angiogenesis that ensures efficient migration of inflammatory cells to the site of insult and communication with adaptive immunity. Besides cytokines, mechanical changes and matrix stiffness, both of which are massively altered during acute and chronic inflammation, have recently been identified as major regulators of endothelial vascular morphogenesis.

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Zertifizierung beantragt für CME Punkte bei der Ärztekammer Berlin
Es wurden für die Teilnahme am DOG Congress 2025 CME Punkte bei der Ärztekammer Berlin beantragt.