The symposium will be opened by Prof. Lois Smith, Harvard Medical School, Boston, who has developed the mouse model of oxygen-induced retinopathy in the 1990s. This model was used to lay the foundations of intravitreal anti-VEGF treatment and has thus had a tremendous impact on our current clinical treatment of wet AMD, DME and many other retinal diseases. Prof. Mike Sapieha, University of Montreal, Canada, will describe his experience in developing new molecules “beyond VEGF” from an academic laboratory into clinical trials to target unmet needs in retinal disease. Maximilian Gerhardt, Ludwigs-Maximilian University Munich, Germany, will take us onto a journey into the world of inherited retinal diseases and gene therapy and describe how novel target molecules are identified and targeted in clinical trials. The symposium will close with a talk by Ann Hellström, University of Gothenburg, Sweden, who will share her experiences from bringing drugs from the laboratory into clinical trials. Prof. Hellström has designed and conducted several investigator-initiated trials (IITs) in multicenter setting to investigate, amongst others, the role of IGF-1 and omega-3 fatty acids in retinopathy of prematurity (ROP). She is currently leading a clinical trial to investigate dexamethasone eye drops in the prevention of severe ROP. Combined, this symposium will offer stimulating presentations for both clinicians and scientists to show how new ideas can emerge from academic laboratories or clinical settings and find their way through the various steps of pre-clinical and clinical validation into the clinic - and in the end change the way we understand and treat a disease.

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Zertifizierung beantragt für CME Punkte bei der Ärztekammer Berlin
Es wurden für die Teilnahme am DOG Kongress 2023 CME Punkte bei der Ärztekammer Berlin beantragt.