Angiogenesis, Exudation, and Degeneration 2026 – Virtual Edition
A scientific education
Angiogenesis, Exudation, and Degeneration 2026 – Virtual Edition
A scientific education
Bascom Palmer Eye Institute
1120 NW 14th Street, Suite 1563
US - 33136 Miami, Florida
Tel.: +1 (305) 326 6110
Fax: +1 (305) 326 6518
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Basisinformation
Datum07.02.2026, 07:50 - 14:10SpracheEnglischGebühren ab200.00 USDVeranstalterBascom Palmer Eye Institute
OrganisatorBascom Palmer Eye Institute
1120 NW 14th Street, Suite 1563
US - 33136 Miami, Florida
Tel.: +1 (305) 326 6110Fax: +1 (305) 326 6518
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Programm
Course Objectives
Upon completion of this course, participants should be able to:
- Understand new evidence for detailing the pathophysiology in nonexudative age-related macular degeneration.
- Examine new evidence for predicting disease progression in nonexudative age-related macular degeneration.
- Evaluate the benefits and limitations of different imaging and visual function technologies in the diagnosis and clinical management of macular and retinal diseases.
- Incorporate the latest advances in artificial intelligence for the diagnosis and management of retinal diseases.
- Evaluate emerging therapies for the treatment of late nonexudative age-related macular degeneration and review the real-world outcomes following the use of complement inhibitors in clinical practice to better understand the population most likely to benefit from these drugs.
- Evaluate therapies targeting novel disease pathways being investigated in early-stage clinical trials for nonexudative age-related macular degeneration.
- Provide an update on anti-VEGF therapies recently approved and currently in development.
- Appreciate the next generation of therapies for exudative ocular diseases.
- Evaluate emerging therapies for the treatment of inherited retinal degenerations.
Agenda
Saturday, February 7, 2026
7:50 am Welcome and Overview / Pre-Program Test
Philip J. Rosenfeld, Harry W. Flynn, Jr., and Thomas A. AlbiniSession I: AMD: Imaging and Disease Progression
Moderators: Giovanni Gregori, Philip J. Rosenfeld, and Zohar Yehoshua
Panelists: Christine A. Curcio, Emily Y. Chew, Aaron Y. Lee, Pearse Keane, Viet-Hoan Le, Omar El-Mulki, Ruikang (Ricky) Wang, Yunchan Hwang, Alessandro Berni, and Robyn Guymer7:00 Retinal, Plasma, and Dietary Xanthophyll Carotenoids in ALSTAR2
Christine A. Curcio7:10 CART Analyses of OCT Classification of AMD
Emily Y. Chew7:20 Deep Learning for AMD: Latest Advances
Aaron Y. Lee7:30 Building a Database of Patients with Early and Intermediate AMD and Long-Term Follow-Up
Pearse Keane7:40 Characterizing and Detecting Drusen with Hyporeflective Cores in OCT Images
Viet-Hoan Le7:50 Do Calcified Drusen and Drusen with Hypo-reflective Cores Predict Disease Progression from iAMD to Large HyperTDs?
Omar El-Mulki8:00 OCTA Imaging of Choriocapillaris in AMD: Practical Considerations
Ruikang (Ricky) Wang8:10 Choriocapillaris Hemodynamic Impairment in Hypertransmission Defects: VISTA OCTA
Yunchan Hwang8:20 Novel Clinical Trial Designs for Intermediate AMD
Alessandro Berni8:30 Nanosecond Laser Treatment Allows the Progressive Loss of the OCT Outer Retinal Bands in iAMD Eyes Without Coexistent RPD
Robyn GuymerSession II: Photoreceptors and AI in AMD
Moderators: Omer Trivizki, Jaclyn Kovach, and Philip J. Rosenfeld
Panelists: SrinVas R. Sadda, Giovanni Staurenghi, Karl Csaky, Amitha Domalpally, Justis P. Ehlers, Ursula Schmidt-Erfurth, Barbara Blodi, David Eichenbaum, Diana V. Do, and Marc Steffen Schmitz-Valckenberg8:40 Validation of Photoreceptor Metrics for AMD Using AOSLO
SriniVas R. Sadda8:50 Elipsoid Zone Measurement: Pros and Cons
Giovanni Staurenghi9:00 Further Assessments of Cone Structure – Function in Non-Foveal Geographic Atrophy
Karl Csaky9:10 Methods for Assessing Photoreceptor Loss in GA
Amitha Domalpally9:20 The Impact of Pseudodrusen on Ellipsoid Zone Integrity Measures in Dry AMD
Justis P. Ehlers9:30 Accuracy and Reliability of AI-based Assessment of Ellipsoid Zone (EZ) Loss and Thinning in Geographic Atrophy (GA)
Ursula Schmidt-Erfurth9:40 Use of an AI Algorithm by Retina Specialists in Prescreening GA Patients for Possible Trial Enrollment
Barbara Blodi9:50 Automated Image Aggregation & AI Analysis Combined with Clinical Data (EMR) in Geographic Atrophy for Improved Candidate Selection for Clinical Trials
David Eichenbaum10:00 AI in GA: Learnings from the Pegcetacoplan Clinical Program
Diana V. Do10:10 AI-Powered Prediction of Retinal Function by OCT Imaging in Geographic Atrophy
Marc Steffen Schmitz-ValckenbergSession III: Geographic Atrophy in AMD
Moderators: Philip J. Rosenfeld, Omer Trivizki, and Jesse Sengillo
Panelists: Roy Schwartz, Seung-Young Yu, Gemmy Cheung Chui Ming, Giselle Herrera, Sara Beqiri, Caroline Baumal, Glenn J. Jaffe, and David R. Lally10:20 A Simplified Severity Scale for GA
Roy Schwartz10:30 Imaging-Based Prediction of Geographic Atrophy Progression Using En Face OCT and FAF
Seung-Young Yu10:40 Incident GA in the Fellow Eye of Patients Presenting with Unilateral Exudative AMD
Gemmy Cheung Chui Ming10:50 Measuring Enlargement Rates of Large Choroidal Hypertransmission Defects over a Wide Range of Lesion Sizes in AMD
Gissel Herrera11:00 The Symmetry of Atrophy Enlargement in AMD Eyes with Bilateral Atrophy
Sara Beqiri11:10 Can Visual Acuity be Estimated from Multimodal Imaging of GA in AMD?
Caroline Baumal11:20 Correlation of Foveal Invasion with Visual Function at Baseline in the Regeneron SIENNA Geographic Atrophy C5 Inhibitor Trial
Glenn J. Jaffe11:30 Controversy in Micronutrient Use in GA
David R. LallySession IV: Emerging Therapies for Non-Exudative AMD
Moderators: Nicolas A. Yannuzzi, Philip J. Rosenfeld, and Omer Trivizki
Panelists: Nancy M. Holekamp, Omer Trivizki, Ivan Lylyk, Mario Saravia, David N. Zacks, Jayakrishna Ambati, Roger A. Goldberg, Arshad M. Khanani, and Frank G. Holz11:40 3-D Pre-Clinical Models Support a Perfusion-Based Hypothesis for AMD
Nancy M. Holekamp11:50 Correlations Between Ophthalmic Artery Stenoses and AMD Severity
Omer Trivizki12:00 pm Performing Ophthalmic Artery Angioplasty in a Cohort of Patients with Geographic Atrophy Secondary to Non-Exudative Age-Related Macular Degeneration (AMD)
Ivan Lylyk12:05 A Feasibility Study of Balloon Angioplasty for the Treatment of Ophthalmic Artery Stenoses in Patients with Geographic Atrophy
Mario Saravia12:10 Fas Inhibition With ONL1204 Ophthalmic Solution for the Treatment of Geographic Atrophy: Results from a Phase 1b Study
David N. Zacks12:15 Inflammasome Inhibition with Kamuvudine K8: A Phase II Clinical Trial in Bilateral Geographic Atrophy
Jayakrishna Ambati12:25 Results from the Phase 2 MAGNIFY TRIAL: Oral Zervimesine for the Treatment of Geographic Atrophy
Roger A. Goldberg12:35 Results from the Phase 2b/3 SIGLEC Trial: AVD-104 in the Management of Geographic Atrophy from Age-Related Macular Degeneration
Arshad M. Khanani12:45 Vision Restoration with the PRIMA System in Geographic Atrophy Due to AMD
Frank G. HolzSession V: FDA-Approved Therapies for the Treatment of Non-Exudative AMD
Moderators: Thomas A. Albini, Maura Di Nicola, and Philip J. Rosenfeld
Panelists: Eleonora Lad, Nathan C. Steinle, Lawrence Singerman, Mathew MacCumber, Hasenin Al-khersan, Mengxi Shen, and Philip J. Rosenfeld12:55 LIGHTSITE IIIB: An Open-Label, Prospective, Multi-Center Extension Study to Assess the Long-Term Safety and Efficacy of Photobiomodulation in Subjects with Dry Age-Related Macular Degeneration
Eleonora Lad1:05 Factors Affecting GA Progression and Vision Loss in OAKS and DERBY Trials
Nathan C. Steinle1:15 24-Month Results from the GALE Open- Label Extension Study: 48 Months of Continuous Pegcetacoplan
Lawrence Singerman1:25 Real-World Visual Acuity and Safety Outcomes from Using Complement Inhibitors for GA in AMD
Mathew MacCumber1:35 Real-World Anatomic Outcomes from Using Complement Inhibitors for GA in AMD
Hasenin Al-khersan1:45 Real-World Efficacy of Pegcetacoplan Over Two Years
Mengxi Shen1:55 Changes in Retinal and Optic Nerve Thickness Measurements Associated with Pegcetacoplan Therapy
Philip J. RosenfeldSession VI: Imaging, Microperimetry, and Emerging Therapies for Exudative AMD
Moderators: Lawrence Singerman, Luis J. Haddock, and Philip J. Rosenfeld
Panelists: Giuseppe Querques, David Sarraf, Usha Chakravarthy, Monika Fleckenstein, Mark R. Barakat, Charles C. Wykoff, Allen C. Ho, Tong (Linda) Li, Arshad M. Khanani, and Rishi P. Singh2:05 Fibrogliosis in Age-Related Macular Degeneration: A New Mechanistic Perspective
Giuseppe Querques2:15 Type 4 MNV: A New Addition to the OCT Classification of Neovascular AMD
David Sarraf2:25 Can iRORA and cRORA Definitions be Applied to Detect Macular Atrophy in Treated nAMD: Findings from the 5T BIG Study
Usha Chakravarthy2:35 Retinal Sensitivity Associated with Type-1 Macular Neovascularization
Monika Fleckenstein2:45 OPTIC Trial: Long-Term Outcomes with Ixo-vec in nAMD
Mark R. Barakat2:55 Ixoberogene Soroparvovec (Ixo-vec) Intravitreal Gene Therapy for Neovascular AMD: 2-year Efficacy and Safety Results from the Phase 2 LUNA Study
Charles C. Wykoff3:05 Expanded One Year Results of a Phase 2 Pharmacodynamic Study: Subretinal Delivery of Investigational Gene Therapy Sura-vec (ABBV-RGX-314) for Neovascular AMD
Allen C. Ho3:15 Subretinal LX102 Gene Therapy for Neovascular Age-Related Macular Degeneration (nAMD): Results of a Randomized, Active-Controlled Phase 2 Trial
Tong (Linda) Li3:25 Long-Term Follow-Up from the PRISM Study: 4D-150 for the Treatment of Neovascular AMD
Arshad M. Khanani3:35 Retinal Fluid Dynamics and Treatment Durability in nAMD: Insights from the DAVIO 2 Trial
Rishi P. SinghSession VII: Clinical Therapies for Exudative AMD, Diabetic Retinopathy, and Retinal Vascular Diseases
Moderators: Janet L. Davis, Basil Williams, and Thomas A. Albini
Panelists: Anat Loewenstein, Mark R. Barakat, Veeral S. Sheth, Carl Danzig, Gemmy Cheung Chui Ming, Dante Pieramici, Peter A. Campochiaro, David M. Brown, and John A. Wells3:45 Longitudinal Validation and Real-World Management with Home OCT in Neovascular AMD
Anat Loewenstein3:55 Machine Learning based Volumetric Analysis of nAMD Biomarkers in Tenaya/Lucerne
Mark R. Barakat4:05 12-Month Results from The VOYAGER Study: An Open-Label International Study Using Faricimab in Treatment-Naïve and Previously Treated nAMD and DME Eyes
Veeral S. Sheth4:15 Four-Year Outcomes of Faricimab in nAMD: Safety and Efficacy Results From the AVONELLE-X Long-Term Extension Trial
Carl Danzig4:25 Faricimab for Polypoidal Choroidal Vasculopathy: 1-Year Results from the Phase 3b/4 SALWEEN Trial
Gemmy Cheung Chui Ming4:35 Pagoda End of Study Results: Port Delivery System for the Treatment of Diabetic Macular Edema
Dante Pieramici4:45 Suppression of VEGF-A is Sufficient to Effectively Treat 95% of DME Patients
Peter A. Campochiaro4:55 Safety and Efficacy of Aflibercept 8 mg in Patients With nAMD or DME: Primary Results from the Phase 3b ELARA Trial
David M. Brown5:05 Safety Profile of Aflibercept 8 mg: A Pooled Analysis of the CANDELA, PULSAR, PHOTON, and QUASAR Trials
John A. WellsSession VIII: Diabetic Retinopathy and Macular Telangiectasia Type 2
Moderators: Harry W. Flynn, Jr., Justin H. Townsend, and William E. Smiddy
Panelists: Sandy Wenting Zhou, Toshinori Murata, Jennifer K. Sun, Michael S. Ip, Jennifer I. Lim, Carl D. Regillo, Andrew J. Barkmeier, Michael A. Singer, Veeral S. Sheth, Dilsher Dhoot, Baruch Kuppermann, Martin Friedlander, and W. Lloyd Clark5:15 AI-Assisted Vascular Biomarker Evaluation in Diabetic Retinopathy On Ultrawide Field Swept-Source Optical Coherence Tomography Angiography - DRIVE Study
Sandy Wenting Zhou5:25 OCTA-Based Analysis of Leakage and Microaneurysms Using Enhanced AI-Inferred Fluorescein Angiography
Toshinori Murata5:35 Association of Retinal Nonperfusion with Vision Threatening Outcomes in Protocol AA
Jennifer K. Sun5:45 Structural OCT Biomarker Responses to Aflibercept, Ranibizumab, and Bevacizumab over 5 years: A Post Hoc Analysis of the DRCR Protocol T
Michael S. Ip5:55 Automated Quantification of the OCT Biomarker Retinal Fluid in Diabetic Macular Edema Treated with Faricimab
Jennifer I. Lim6:05 Danegaptide: A Novel, First-in-Class Oral Therapy for Patients with NPDR - Preclinical and Phase 1b Study Results
Carl D. Regillo6:10 Phase 2 Study Evaluating Short-Term Efficacy of Tonabersat for Diabetic Macular Edema
Andrew J. Barkmeier6:20 Subcutaneous Migaldendranib (MGB) for the Treatment of Diabetic Macular Edema and Neovascular Age-Related Macular Degeneration: 40-Week Study Results from a Phase 2 Clinical Trial
Michael A. Singer6:30 PER-001: A Long-Acting Intravitreal Endothelin Antagonist for Structural and Functional Improvement in Diabetic Retinopathy
Veeral S. Sheth6:40 Suprachoroidal Delivery of Surabgene Lomparvovec (Sura-vec, ABBV-RGX-314): 2-Year Results in Non-Proliferative Diabetic Retinopathy
Dilsher Dhoot6:50 Efficacy and Safety Outcomes with OCS-01 Eye Drops for the Treatment of Diabetic Macular Edema from the DIAMOND Stage 1 Phase 2/3 Trial
Baruch Kuppermann7:00 What's New with MacTel 2?
Martin Friedlander7:10 Timing of Ocular Adverse Events in Pooled Analysis of Two Phase 3 Trials of Revakinagene Taroretcel-Iwey (NT-501) in MacTel Type 2
W. Lloyd ClarkSession IX: Inherited Retinal Degenerations
Moderators: Byron L. Lam, Sander R. Dubovy, and Ninel Z. Gregori
Panelists: Robert Bhisitkul, David S. Boyer, Peter K. Kaiser, Kenneth C. Fan, Nadia K. Waheed, Byron C. Lam, and Fenghua Wang7:20 Phase 1 WALLABY/PLATYPUS Studies of Intravitreal VP- 001 in PRPF31 Mutation-Associated Retinal Pigmentosa
Robert Bhisitkul7:25 Ray Therapeutics Phase 1 Trial of Optogenetics for Retinitis Pigmentosa
David S. Boyer7:35 LUCE: A First-in-Human Phase I/II Trial of Dual AAV8.MYO7A Gene Therapy in Subjects with Usher Syndrome Type1B Retinitis Pigmentosa
Peter K. Kaiser7:45 The TEASE Program: Evaluating Gildeuretinol in Early to Advanced Stages of Stargardt Disease
Kenneth C. Fan7:55 Clinical Trial and Imaging Results of a Phase 2 Study on RPGR Gene Therapy in X-Linked Retinitis Pigmentosa
Nadia K. Waheed8:05 Safety and Efficacy of MCO-010 Phase 2 Optogenetic Therapy in Patients with Stargardt Disease
Byron C. Lam8:15 Safety and Efficacy of LX101 Gene Therapy in Chinese Patients with RPE65-Inherited Retinal Dystrophy: Results of the Phase 3 Trial
Fenghua Wang8:25 Post-Program Test and Closing Remarks 8:30 Meeting Adjourns -
Gebühren
Fachärzte/-innenGebühren ab200,00 USDÄrzte/-innen in WeiterbildungGebühren ab200,00 USDAll registrations must be received no later than Thursday, February 5th, 2026 at 3:00 pm (ET).
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Buchung / Anmeldung
Registration required. Please contact the organizer for further information.
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Zertifizierung
Zertifizierung beantragt für CME Punkte bei der Sonstige
The University of Miami Leonard M. Miller School of Medicine designates this live activity for a maximum of 13.0 AMA PRA Category 1 Credits™.