Neurotrophic keratopathy (NK) is a serious and rare degenerative corneal disease caused by impairment in the trigeminal innervation of the cornea. Epithelial breakdown can lead to ulceration, melting of the stroma, and ultimately to corneal perforation. Significant damage may be avoided with appropriate therapeutic options when given in a timely manner.

The goal of this CME monograph is to educate eye care providers on the latest scientific understanding of NK, including:

• clinical manifestations and complications;
• conditions associated with the development of NK and populations at risk;
• the importance of early detection and early management;
• screening and diagnostic strategies; and
• optimal management strategies including emerging treatments and the latest clinical data (safety, efficacy, and mechanism of action [MOA]).