Pre-Meeting 1: New Member Spotlight

Tuesday, August 25, 8:00–9:30 pm ET

Welcome & Announcements

Program Committee

Session 1.1: Age-related Macular Degeneration: A Focus on Durability

Moderator: David Brown, MD

Panelists: Anita Agarwal, MD; Emily Chew, MD; Bailey Freund, MD; Joo Yong Lee, MD, Charles Wykoff, MD

Presenters: David Eichenbaum, MD; Arshad Khanani, MD; Benjamin Kim, MD

Key Learnings From the Phase 2 Ladder Trial of the Port Delivery System With Ranibizumab (PDS) in Patients With nAMD

David Eichenbaum, MD

Updated Results of Phase 1b Study of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate w Durability, in wAMD, DME, and RVO

Arshad Khanani, MD

Prolonged Intraocular Residence of a Fourth Generation Compstatin Complement C3 Inhibitor Supports Its Clinical Development for GA

Benjamin Kim MD

Live Panel Q/A

Mrinali Gupta, MD

Session 1.2: Potpourri: Diabetes, Imaging & Inflammation 

Moderator: SriniVas Sadda, MD

Panelists: Brandon Lujan, MD; David Sarraf, MD; Eliott Sohn, MD; Kimberly Stepien, MD; Akitaka Tsujikawa, MD

Presenters: Dilraj Grewal, MD; Satoru Kase, MD; Ajay Kuriyan, MD; Zofia Michalewska, MD; Andreas Pollreisz, MD

Correlation of Macular Vessel Density and Vision in Proliferative Diabetic Retinopathy: Development and Application of an Automated Deep Neural Network for Fluorescein Angiography Vessel Detection

Ajay Kuriyan, MD

Longitudinal Changes of Microvascular Perfusion and Neurodegeneration in Early Type 2 Diabetic Retinal Disease

Andeas Pollreisz, MD

Swept Source OCT Angiography in Eyes After Scleral Buckling

Zofia Michalewska, MD, PhD

Choroidal Macrovessel: A Multimodal Imaging Analysis

Satoru Kase, MD

Evaluating the True Rate of Recurrence of Non-Infectious Posterior Segment Uveitis Following Treatment with an Injectable FA insert

Dilraj Grewal, MD

Live Panel Q/A

Mrinali Gupta, MD

Session 1.3: Fellow Award 

Moderator: Prithvi Mruthyunjaya, MD

Panelists: Amani Fawzi, MD; Deeba Husain, MD

Margherio Awardee Presentation: Progression of Geographic Atrophy with Subsequent Exudative Neovascular Disease in Age-related Macular Degeneration: AREDS2 Report 23

Christopher Hwang, MD

Panelists

Emily Chew, MD; Christopher Hwang, MD; Prithvi Mruthyunjaya, MD

Live Panel Q/A

Session 1.4: Surgery with the Next Generation of Vitreoretinal Surgical Stars

Moderator: Kourous Rezai, MD

Panelists: Peter Campbell, MD; Steve Charles, MD; Kimerbly Drenser, MD, Eric Nudleman, MD, Kirk Packo, MD

Presenters: Lisa Faia, MD; Ali Khan, MD; Michael Klufas, MD; Jayanth Sridhar, MD; Yoshihiro Yonekowa, MD

Clinical Outcomes in Bilateral Sequential Rhegmatogenous Retinal Detachment

Michael Klufas, MD

Characteristics and Surgical Outcomes of Rhegmatogenous Retinal Detachment in Elderly Patients

Yoshihiro Yonekawa, MD

ERM Surgery Following Prior Primary RRD Repair: Optical Coherence Tomography Features and Surgical Outcomes

Ali Khan, MD

Lens and Peripheral Retinal Relationships During Vitrectomy: Comparison of 23, 25, and 27-gauge Vitrectomy and Curved Endolaser pProbes

Jayanth Sridhar, MD

Long-Term Outcomes of Sutureless Intrascleral Fixation of Intraocular Lens with Pars Plana Vitrectomy in Patients with Posterior or Panuveitis

Lisa Faia, MD

Live Panel Q/A

Mrinali Gupta, MD

Pre-Meeting 2: Clinical Trials - The Cutting Edge

Tuesday, September 8, 8:00–9:30 pm ET

Welcome and Announcements

Program Committee

Session 2.1.1: Trials on the Edge - Can We Raise the Bar for AMD?

Moderators: Jennifer Lim, MD; David Zacks, MD

Panelists: Susan Bressler, MD; Carl Csaky, MD; Dante Pieramici, MD

Author Panelists:  Sumit Shah, MD; Robert Avery, MD; Eleanora Lad, MD; Glenn Jaffe, MD

Prophylaxis Intravitreal Aflibercept against Conversion to Neovascular Age-Related Macular Degeneration in High Risk Eyes (PRO-CON): 24 Month Results

Sumit Shah, MD

Preliminary Findings from a Phase 1 Trial Evaluating the Safety, Tolerability and Biological Activity of OTX-TKI, a Hydrogel-Based, Sustained-Release Intravitreal Axitinib Implant, in Subjects with Neovascular Age-Related Macular Degeneration (nAMD)

Robert Avery, MD

Effect of Dual Angiopoietin-2/VEGF-A Inhibition with Faricimab on Macular Anatomy in the STAIRWAY Ph2 Study of nAMD

Eleanora Lad, MD

Macular Atrophy (MA) in the Phase 2 Ladder Trial

Glenn Jaffe, MD

Live Panel Q/A

Session 2.1.2: Trials on the Edge - Diabetes and More 

Moderators: Shlomit Schaal, MD; Cynthia Toth, MD

Panelists: Lloyd Aiello, MD,  Jennifer Sun, MD

Author Panelists:  Nathan Steinle, MD, Ingrid Scott, MD, Pauline Merrill, MD

Treatment Effect of Intravitreal Aflibercept Injection by Baseline Factors in Moderately Severe-to-Severe NPDR in PANORAMA

Nathan Steinle, MD 

Study of COmparative Treatments in REtinal Vein Occlusion 2 (SCORE2) Month 48 Results

Ingrid Scott, MD

Results from the Phase 3 PEACHTREE Clinical Trial: Systemic Therapy and the Efficacy of CLS-TA, a Post-Hoc Analysis

Pauline Merrill, MD

Live Panel Q/A

Session 2.2: Retina Society Fellow Research Award

Moderator: Prithvi Mruthyunjaya, MD

Retina Research Awardee: Elizabeth Rossin, MD, PhD; Presentation:  Structure-based network analysis of viral proteins reveals potential epitopes for vaccine targeting in SARS-CoV-2
Sponsor: Lucia Sobrin, MD

Mentor: Gaurav Gaiha, MD

Panelists: Rajendra Apte, MD; Gaurav Gaiha, MD; Elizabeth Rossin, MD, PhD; Adrienne Scott, MD

Live Panel Q&A

Session 2.3: Pediatrics 

Moderator: Antonio Capone, MD

Panelists: Paul Chan, MD; Philip Ferrone, MD; Baker Hubbard, MD; Thomas Lee, MD

Author Panelists: Nina Berrocal, MD; Cynthia Toth, MD; Kim Jiramongkolchai, MD

Retinoschisis in Coats Disease

Nina Berrocal, MD 

Macular OCT Characteristics at 36 weeks Postmenstrual Age in a Cohort of Preterm Infants Examined for Retinopathy of Prematurity

Cynthia Toth, MD

Lower Fetal Hemoglobin Levels at 31- and 34-weeks Postmenstrual Age is Associated with the Development of Retinopathy of Prematurity

Kim Jiramongkolchai, MD

Live Panel Q/A

Session 2.4.1: Trials on the Edge - Promising Translational Advances 

Moderators: Jennifer Lim, MD; Andrew Schachat, MD

Panelists: Aaron Nagiel, MD; Thiran Jayasundara, MD

Author Panelists:  David Zacks, MD; Baruch Kuppermann, MD; Jose-Alain Sahel, MD; Stephen Russell, MD

Absence of Fas receptor signaling reduces photoreceptor cell death and improves retinal function in a mouse model of P23H auto dominant RP

David Zacks, MD

Intravitreal Injection of Allogeneic Human Retinal Progenitor Cells for the Treatment of RP: A Prospective Randomized Controlled Phase 2

Baruch Kuppermann, MD

Signs of functional vision recovery in an advanced stage RP patient after optogenetic therapy

Jose-Alain Sahel, MD

Five-year update for the phase 3 voretigene neparvovec-rzyl study in biallelic RPE65 mutation associated inherited retinal disease

Stephen Russell, MD

Live Panel Q/A

Session 2.4.2: Trials on the Edge - Focus on Gene Therapies

Moderators: Szilard Kiss, MD, Cynthia Toth, MD

Panelists: Peter Campochiaro, MD, Christine Kay, MD, Mark Pennesi, MD

Author Panelists: Ninel Gregori, MD, Joseph Martel, MD, Brian Joondeph, MD, Nancy Holekamp, MD

Choroideremia Gene Therapy: Phase 2 Clinical Trial 48 Month Results and Overview

Ninel Gregori, MD

First Results of a Photovoltaic Subretinal Prosthesis for Restoration of Central Vision in Atrophic Dry Age-Related Macular Degeneration in the United States

Joseph Martel, MD

ADVM-022 Intravitreal Gene Therapy for Neovascular AMD -  Phase 1 OPTIC Study Update

Brian Joondeph, MD

Suprachoroidally delivered non-viral DNA nanoparticles transfect chorioretinal cells in non-human primates and rabbits

Nancy Holekamp, MD

Live Panel Q/A

Meeting 3: RS2020 VR Live

Monday, September 21, 8:00–10:00 pm ET

Session 3.1: Interpreting Signals for AMD Therapies

Moderators: Sunir Garg, MD; Steven Yeh, MD

Panelists: Richard Kaiser, MD; Darius Moshfeghi, MD

Author Panelists: Daniel Roth, MD; Andre Witkin, MD; Caroline Baumal, MD; Thomas Albini, MD

Reduced Incidence of Post-Injection Endophthalmitis with Pre-filled Syringes

Daniel Roth, MD

Occlusive retinal vasculitis following intravitreal brolucizumab for exudative age-related macular degeneration

Andre Witkin, MD

Retinal vasculitis and intraocular inflammation after intravitreal injection of brolucizumab

Caroline Baumal

Abicipar Phase 2 MAPLE Trial Demonstrates Improved Safety for Patients with nAMD Following a Modified Manufacturing Process

Thomas Albini, MD

Live Panel Q&A

Session 3.2.1: Medical Controversy: Which Anti  VEGF Agent do I choose?

Moderators: Jeffrey Heier, MD; Allen Ho, MD

Panelists: Jason Hsu, MD; Reginald Sanders, MD

Author Panelists: Peter Kaiser, MD; David Lally, MD; Diana Do, MD

Visual and anatomical outcomes by q12w/q8w status in the HAWK and HARRIER studies of brolu. versus aflibercept in neovascular AMD

Peter Kaiser, MD

A comparison of the efficacy of brolu and aflibercept in eyes with early persistent retinal fluid: 96-week results from the HAWK and HARRIER studies

David Lally, MD

Absence of Safety Signal for Occlusive Retinal Vasculitis with Intravitreal Aflibercept Injection

Diana Do, MD

Live Panel Q&A 

Session 3.2.2: Retinal Detachment Surgical Controversy: SB, PPV or Something Else?

Moderators:  Mark Johnson, MD; Judy Kim, MD

Panelists: Edwin Ryan, MD; Michael Trese, MD; Lejla Vajzovic, MD

Author Panelists: Susanna Park, MD; Thomas Wubben, MD; Rajeev Muni, MD

Interesting Case - Unexplained progressive vision loss after successful retinal detachment repair

Susanna Park, MD

Pars plana vitrectomy versus combined pars plana vitrectomy-scleral buckle versus scleral buckle for repair of primary RRD

Thomas Wubben, MD

Retinal Displacement following Pneumatic Retinopexy vs Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment (ALIGN STUDY)

Rajeev Muni, MD

Live Panel Q/A

Sessions 3.3: The Evolution of Vitreoretinal Surgery 

Moderators:  Donald D’Amico, MD; George Williams, MD

Panelists: Stanley Chang, MD; Thomas Aaberg Jr, MD

Author Panelists: Nicole Koulisis, MD; Christina Weng, MD; Natalia Figueiredo, MD; Rahul Khurana, MD; Mauricio Maia, MD

Functional and Anatomic Outcomes of the … Consortium of Autologous Retinal Transplantation for Primary, Refractory, and Macular Hole Retina 

Nicole Koulisis, MD

Autologous Retinal Transplant in a Macular Hole-associated Total Rhegmatogenous Retinal Detachment 

Surgical Video - Christina Weng, MD

Interesting Case - Paracentral Scotoma after Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

Rahul Khurana, MD

Longitudinal Assessment of Ellipsoid Zone Recovery using En Face OCT after Retinal Detachment Surgery

Natalia Figueiredo, MD

Association of Weight-Adjusted Caffeine and β-Blocker Use With Ophthalmology Fellow Performance During Simulated Vitreoretinal Microsurgery

Mauricio Maia, MD

Live Panel Q/A

Session 3.4: Retinal Research Foundation Award / Schepens Lecture

Moderator and Introductions: Bernard Doft, MD; Paul Sternberg, MD

Awardee: Russell Van Gelder, MD, PhD - Prospects for vision restoration in outer retinal degeneration

Panelists: Harry Flynn, MD; Joan Miller, MD; Jose Pulido, MD

Live Panel Q/A 

Session 3.5: New Tools and Techniques Vitreoretinal Surgery

Moderators: Dean Eliott, MD; Tarek Hassan, MD

Panelists: David Chow, MD; Gaurav Shah, MD

Author Panelists: Maria Berrocal, MD; Tomasz Stryjewski, MD; Scott Walter, MD; Yanneck Leiderman, MD; Prithvi Mruthyunjaya, MD

Retinal Detachment Repair with 27g Vitrectomy with 20,000 c/m Probe

Surgical Video- Maria Berrocal, MD

PYK-1105: Pre-Clinical Evaluation Of A Novel Biodegradable Vitreous Substitute For Retinal Tamponade

Tomasz Stryjewski, MD

Management of Proliferative Vitreoretinopathy with Intravitreal Methotrexate using a Treat-and-Extend Protocol

Scott Walter, MD

Surgical Guidance in Pars Plana Vitrectomy Using Deep Learning and Computer Vision 

Yannek Leiderman

The Exudative and Rhegmatogenous Retinal Detachment:  Getting Answers

Surgical Video - Prithvi Mruthyunjaya, MD

Live Panel Q/A

Session 3.6: The Promising AMD Drug and Technology Pipeline

Moderators: David Boyer, MD; Peter Kaiser, MD

Panelists:  Alice Lyon, MD; Alexander Brucker, MD

Author Panelists: Carl Regillo, MD; Allen Chiang, MD; David Brown, MD; Anat Loewenstein, MD

Avacincaptad Pegol, A Novel C5 Inhibitor, Significantly Reduces the Mean Rate of Geographic Atrophy Growth in a Pivotal  Clinical Trial

Carl Regillo, MD

Assessment of Progression of Geographic Atrophy in the FILLY Study

Allen Chiang, MD

Suprachoroidal CLS-AX (axitinib injectable suspension), as a Potential Long-Acting Therapy for Neovascular Age-Related Macular Degeneration (nAMD)

David Brown, MD

Usability and Quality of Retinal Images Captured by a Self-Operated, Home-based Optical Coherence Tomography (OCT) System

Anat Loewenstein, MD 

Live Panel Q/A 

Meeting 4: RS2020 VR Live  

 Tuesday, September 22, 8:00–10:00 pm ET

  Session 4.1: Oncology 2020

Moderators: Ivana Kim, MD; Tara McCannel, MD

Author Panelists: David Abramson, MD; Anthony Daniels, MD; Carol Shields, MD; Prithvi Mruthyunjaya, MD; Timothy Murray, MD

Circumscribed choroidal hemangioma: Visual outcome in the pre-photodynamic therapy (PDT) vs PDT eras in 458 cases

Carol Shields, MD

Treatment of Retinoblastoma Patients with 13q Deletion Syndrome in the Intrarterial and Intravitreal Era

David Abramson, MD

Vitreous proteomics correlates with gene expression profiling in uveal melanoma

Prithvi Mruthyunjaya, MD 

Vitreoretinal Surgical Management of Small Choroidal Melanoma: 5-year outcomes in patients avoiding radiotherapy

Timothy Murray, MD 

Impact of different initial systemic staging imaging strategies on metastasis …: The Melanoma of the Uvea Staging Imaging Consortium (MUSIC)

Anthony Daniels, MD

Live Panel Q/A

Session 4.2  Late Breakers: Age-related Macular Degeneration and Diabetic Retinopathy

Moderators:  Mark Blumenkranz, MD, Allen Ho, MD

Panelists: Jorge Arroyo, MD, Ivan Suner, MD

Author Panelists: Carl Awh, MD, Charles Wykoff, MD, Hani Salehi-Had, MD, Jeffrey Heier, MD

Primary Analysis Results of the Phase 3 Archway Trial of the Port Delivery System with Ranibizumab (PDS) for Patients With nAMD

Carl Awh, MD

Gene Therapy with RGX-314 for Neovascular AMD: New Results from the Ongoing Phase I/IIa Study

Charles Wykoff, MD

Intraocular Inflammation, Vasculitis & Vascular Occlusion in the HAWK & HARRIER Trials: Findings of the Safety Review Committee

Jeffrey Heier, MD

Effect of  Vitrectomy and Panretinal Photocoagulation versus Intravitreous Aflibercept on Visual Acuity in Patients with Vitreous Hemorrhage from Proliferative Diabetic Retinopathy:  A Randomized Clinical Trial

Andrew Antoszyk, MD

Session 4.3  RetinoVascular Correlations

Moderators: Adrienne Scott, MD, Pat Wilkinson, MD

Panelists: Peter Hovland, MD, Keith Warren, MD

Author Panelists: Jennifer Lim, MD, Michael Ip, MD, Anita Agarwal, MD

Live Panel Q/A

Risk factors for retinal thinning in sickle cell versus control eyes: Analysis of a prospective study using SDOCT Imaging 

Jennifer Lim, MD

Correlation of Best Corrected Visual Acuity and Central Subfield Thickness in Macular Edema Due to RVO, Diabetic Retinopathy and Uveitis 

Michael Ip, MD

Retinal Vasculopathy in a 40-year-old female

Anita Agarwal, MD

Live Panel Q/A

Session 4.4: The Retina Society Gass Award

Introductions: Bernard Doft, MD; Stuart Fine, MD

Awardees:  Maureen Maguire, PhD, FARVO, and Daniel Martin, MD:

CATT Tales: 15 Years of Science, Politics, and Persistence

Panelists: Robert Avery, MD, Neil Bressler, MD, Philip Rosenfeld, MD

Live Panel Q/A 

Session 4.5  The Evolving Paradigm for Diabetic Retinopathy

Moderators:  Lloyd Aiello, MD, William Mieler, MD

Panelist: Andrew Moshfeghi, MD, Jennifer Sun, MD

Author Panelists: Quan Nguyen, MD, Sophia Bakri, MD, Ehsan Rahimy, MD, David Boyer, MD, Jason Hsu, MD

Has the Time Come to Re-evaluate the Treatment Paradigm for Diabetic Retinopathy?

Quan Nguyen, MD

Clinical Significance of DR Improvement: A Meta-Analysis of Vision and Anatomic Outcomes in Five Clinical Trials Evaluating IVT Ranibizumab

Sophie Bakri. MD

Progression to Proliferative Diabetic Retinopathy in Nonproliferative Diabetic Retinopathy Eyes without Diabetic Macular Edema in the United States

Ehsan Rahimy, MD

Intravitreal Aflibercept Injection for Nonproliferative Diabetic Retinopathy: Results from the PANORAMA Study

David Boyer, MD 

Outcomes of Eyes with Diabetic Macular Edema that are Lost to Follow-up after Anti-Vascular Endothelial Growth Factor Therapy

Jason Hsu, MD

Live Panel Q/A

Session 4.6  The Future of Retina and RS2020VR Highlights

Moderators: Jeffrey Heier, MD; Allen Ho, MD

Panelists: Julia Haller, MD; Mark Humayan, MD; David Parke, MD, Allison Shuren, JD, James Vander, MD;

Author Panelists: Jiong Yan, MD; Itay Chowers, MD; Aleksandra Rachitskaya, MD

Medical-Legal and Ethical Considerations During the COVID-19 Pandemic

Interesting Case - Itay Chowers, MD - Risks of SARS-CoV-2 Transmission to Medical Staff and Patients froman Exposure to a COVID-19-Positive Ophthalmologist

Provider Ratings and Patient, Disease, and Appointment Factors

Live Panel Q/A

END PROGRAM and ANNOUNCEMENTS