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7th International AMD-Symposium

76530 Baden-Baden, Baden-Württemberg, Deutschland
Fortbildung

7th International AMD-Symposium

7th International DOG-Symposium on Age-Related Macular Degeneration - Exploring new pathways – developing new therapies -

Datum:
20.09.2019, 08:30 - 21.09.2019, 17:30
Veranstalter:
Augenabteilung am St. Franziskus-Hospital Münster
Kurzbeschreibung:
The 7th International AMD-Symposium will be held in Baden-Baden, Germany. Major topics concern age-related macular degeneration and applied science in AMD respectively. The symposium is directed by Professor Daniel Pauleikhoff.
Fortbildungspunkte: beantragt

Fachärzte

Max. Teilnehmer: unbegrenzt
Gebühren ab: 370,00 EUR
EarlyBird bis 01.08.2019: 340,00 EUR

Hinweis:
incl. VAT and excl. foreign transfer fees

Ärzte/-innen in Weiterbildung

Max. Teilnehmer: unbegrenzt
Gebühren ab: 370,00 EUR
EarlyBird bis 01.08.2019: 340,00 EUR

Hinweis:
incl. VAT and excl. foreign transfer fees

Studenten/-innen

Max. Teilnehmer: unbegrenzt
Gebühren ab: 170,00 EUR
EarlyBird bis 01.08.2019: 140,00 EUR

Hinweis:
Student*, unemployed person*

* presentation of appropriate proof of status is required at the time of online-registration or may also be faxed to +49 211 / 593560; otherwise the regular fee will be charged.

Sonstige

Max. Teilnehmer: unbegrenzt
Gebühren ab: 220,00 EUR
EarlyBird bis 01.08.2019: 190,00 EUR

Hinweis:
Resident*, Fellow*

* presentation of appropriate proof of status is required at the time of online-registration or may also be faxed to +49 211 / 593560; otherwise the regular fee will be charged.
Bemerkungen:
Diese Veranstaltung findet jährlich statt und bietet Fortbildungsmöglichkeiten für Fachärzte, Ärzte/-innen in Weiterbildung, Studenten/-innen und Sonstige.
Die Zertifizierung wurde bei der Ärztekammer Westfalen-Lippe beantragt.
Veranstaltungsnummer: 28561
Zertifizierung: beantragt
Gebühren ab: ab 140,00
Frühbucher: bis 01.08.2019
140,00 EUR
verfügbare Plätze: unbegrenzt
Sprache: Englisch
 
Vom Veranstalter gemeldetes Programm:

 

Friday, 20th September 2019

 

08:30 Opening remarks and welcome
Daniel Pauleikhoff (Münster)
Frank G. Holz (Bonn)

 

08:45 - 10:15 1st Session - AMD basics
Moderators:
SriniVas Sadda (Los Angeles/USA)
Steffen Schmitz-Valkenberg (Bonn)

 

1 L
Alan C. Bird (London/GB)
Why the macula? – Learnings from the MacTel project

 

2 L
Philip J. Luthert (London/GB)
Cellular structures - computational biology of the macula

 

3 L
Christine A. Curcio, D. Kar, D.M. Dacey, D.M.G. Anderson, A. Kotnala, K.L. Schey (Birmingham/USA., Seattle/USA, Nashville/USA)
Molecular microarchitecture of macula in health and AMD

 

4 L
Robert Mullins (Iowa City/USA)
Addressing choriocapillaris degeneration in AMD: Cause, consequences, and potential therapies

 

5 L
Sandra Liakopoulos (Cologne/D)
Macular Imaging - Morphology and changes in AMD and aging?

 

6 L
Marius Ueffing (Tübingen/D)
Using cell lines - identify, model and validate AMD risk factors and disease drivers

 

7 P
Anita de Breuk, I.E. Acar, E. Kersten, M.M.V.A.P. Schijvenaars, M.A. Meester-Smoor, C. Delcourt, C.C.W. Klaver,
J. Monés, D. Pauleikhoff, R. Silva, S. Fauser, C.B. Hoyng, M.J.H. Coenen, A.I. den Hollander, EYE-RISK Consortium
(Nijmegen/NL, Rotterdam/NL, Bordeaux/F, Barcelona/E, Münster/D, Coimbra/P, Cologne/D)
Development of a Genotyping Assay for AMD: The EYE-RISK Consortium

 

8 P
Thomas J. Heesterbeek, E.K. de Jong, I.E. Acar, J.M.M. Groenewoud, B. Liefers, C.I. Sánchez,
T. Peto, C.B. Hoyng, D. Pauleikhoff, H.W. Hense, A.I. den Hollander
(Nijmegen/NL, Belfast/GB, Münster/D)
Genetic Risk Score has added value over initial clinical grading stage in predicting disease progression in patients
with non-advanced age-related macular degeneration – The Muenster Aging and Retina Study (MARS)

 

10:15 - 10:45 - Coffee break in the industrial exhibition area

 

 

10:45 - 12:30 2nd Session - Genetics and risk factors of AMD
Moderators:
Carel B. Hoyng (Nijmegen/NL)
Bernhard H.F. Weber (Regensburg/D)

 

 

9 L
Bernhard H.F. Weber (Regensburg/D)
AMD – Searching for targeted therapies

 

10 L
Carel B. Hoyng (Nijmegen/NL)
AMD genotype-phenotype correlation?

 

11 L
Magda A. Meester-Smoor, C.C.W. Klaver (Rotterdam/NL)
EyeRisk Study – risk factors for AMD phenotypes and progression?

 

12 L
Giovanni Staurenghi (Milan/I)
How to differentiate GA phenotypes – the CAM initiative

 

13 L
Frank G. Holz, S. Schmitz-Valckenberg, M. Schmid, G.S. Rubin, H. Dunbar, A. Tufail, D.P. Crabb, A. Binns,
C.I. Sánchez, P. Margaron, G. Normand, M.K. Durbin, U.F.O. Luhmann, P. Zamiri, J. Cunha-Vaz, F. Asmus F, R.P. Finger,
on behalf of the MACUSTAR consortium Intermediate AMD – the Macustar project

 

14 L
Steffen Schmitz-Valkenberg (Bonn/D)
Challenges in phenotyping geographic atrophy

 

15 L
Andrew Lotery, J R. Sutton, S. Khandhadia, G. Menon, C. Bailey, S. Sivasprasad, Q. Mohamed, P. Bishop, P. Charbel Issa,
D. Steel, T. Peto, W. Amoaku, R. Arora, P. Prakash, W. Innes, R. Maclaren, D. Kavanagh
(Southampton/GB, Camberley/GB, Bristol/GB, London/GB, Cheltenham/GB, Manchester/GB, Oxford/GB,
Sunderland/GB, Nottingham/GB, Salisbury/GB, Harlow/GB, Newcastle/GB)
Rare genetic variants in geographic atrophy

 

16 L
Sobha Sivaprasad (London/GB)
Early loss of color vision on drusen and reticular pseudodrusen

 

12:30 - 13:45 - Lunch

 

 

13:45 - 15:45 3rd Session - Complement, inflammation and cellular energetics in AMD
Moderators:
Philip J. Luthert (London/GB)
Marius Ueffing (Tübingen/D)

 

 

17 L
Gregory S. Hageman, C.M. Pappas, R.A. Anstadt, J.Liu, B.L. Williams, N.A. Seager, J.L. Hageman,
M. Zouache, K. Curtin, B.T. Richards (Salt Lake City/USA)
Complement-directed AMD is a distinct, genotype-driven subset of the disease

 

18 L
Bradley D. Gelfand, J. Ambati (Charlottesville/USA)
Inflammasome in AMD

 

19 L
Tim U. Krohne, L. Wang, S. Schmidt, J. Rossa, P.P. Larsen, J.H. Meyer, W.R. Roush, E. Latz, F.G. Holz (Bonn/D, Boston/USA)
NLRP3 inflammasome as a therapeutic target in AMD

 

20 L
Glen Jeffery (London/GB)
Mitochondrial decline precedes phenotype development in the complement factor H
mouse model of retinal degeneration but can be corrected by near infrared light

 

21 L
Imre Lengyel (Belfast/IRL)
Is mineralization a major factor in drusen pathogenesis?

 

22 P
Martin Zinkernagel, D. Zysset, I. Keller, L. Berger, B. Yilmaz, S. Wolf (Bern/CH)
Associations of the intestinal microbiome with AMD

 

23 P
Ilhan Erkin Acar, L. Lores de Motta, M.A. Meester, S. Ajana, D. Pauleikhoff, S. Fauser, C.B. Hoyng,
C. Delcourt, C.C.W. Klaver, T.E. Galesloot, A.I. den Hollander
(Nijmegen/NL, Rotterdam/NL, Bordeaux/F, Münster/D, Cologne/D)
Metabolomics identifies lipoprotein subclasses and dietary metabolites that are associated with AMD: The EYE-RISK Consortium

 

24 P
Yara Lechanteur, T. Heesterbeek, L. Lorés-Motta, T. Schick, M. Daha, L. Altay, S. Liakopoulos, D. Smailhodzic,
A. den Hollander, C. Hoyng, E. de Jong, B. Klevering
(Nijmegen/NL, Cologne/D, Leiden/NL)
Complement activation levels are related to disease stage in AMD

 

25 P
Laura Lorés de Motta, V. Cipriani, F. He, D. Fathalla, S. McHarg, N. Bayatti, I.E. Acar, C.C.B. Hoyng, S. Fauser,
A. Moore, J.R.W. Yates, P. Morgan, E.K. de Jong, A.I. den Hollander, P.N. Bishop, S.J. Clark
(Nijmegen/NL, London/GB Manchester/GB, Cardiff/GB, Cologne/D, Basel/CH, San Francisco/USA, Cambridge/GB,)
Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in AMD

 

26 P
Anja Schlecht, P. Wieghofer, P. Zhang, S. Bonvea, M. Gruber, R. Sankowski, G. Schlunck, H. Agostini, M. Prinz, C. Lange
(Freiburg i.Br./D, Leipzig/D)
Identification of myeloid cell populations at sites of laser-induced choroidal neovascularization by single-cell profiling

 

27 P
Alexa Klettner, K. Winkelmann, A. Brinkmann, T. Käckenmeister, J. Roider (Kiel/D)
Effect of long-term inflammation on viability and function of RPE cells

 

15:45 - 16:15 Coffee break

 

 

16:15 - 17:40 4th Session - Neurobiology of the outer retina I
Moderators:
Deborah A. Ferrington (Minneapolis/USA)
John G. Flannery (Berkley/USA)

 

 

28 L
Thomas Langmann, A. Wolf (Cologne/D)
Microglia as important part of the retina: Its role in AMD

 

29 P
Clemens Lange, A. Schlecht, S. Boneva, J. Wolf, P. Zhang, G. Prinz, R. Horres, F. Bucher, C. Auw-Haedrich,
L. Hansen, A. Stahl, I. Hilgendorf, H. Agostini, P. Wieghofer, G. Schlunck
(Freiburg i.Br./D, Frankfurt/D, Greifswald/D, Leipzig/D)
Transcriptomic characterization of human choroidal neovascular membranes
identifies calprotectin as a novel biomarker for patients with AMD

 

30 L
Rajendra S. Apte (St. Louis/USA)
Animal model for AMD interfering lipid trafficking

 

31 P
Christian Grimm, F. Storti, T. Hornemann, A. den Hollander, C. Maugeais
(Schlieren/CH, Nijmegen/NL, Basel/CH)
Impaired function of the lipid transporters ABCA1 and ABCG1 in the RPE leads to an AMD-like phenotype in mice

 

32 L
Nicolas Bazan (New Orleans/USA, Stockholm/S)
Elovanoids are novel photoreceptor survival signals relevant to AMD

 

33 L
Clare Futter (London/GB)
Lysosome dysfunction in the RPE and its role in early AMD

 

34 L
Gerard A. Lutty, S. Ogura, R. Baldeosingh, D.S. McLeod, M.M. Edwards, I.A. Bhutto (Baltimore/USA)
Mast cell involvement in geographic atrophy

 

 

17:40 - 18:00 Lecture in memory of Gerhard Zinser
Moderator:
Frank G. Holz
Daniel Pauleikhoff

 

35
Josef F. Bille (Heidelberg/D)
Past, present and new horizons in imaging analysis - The heritage of Gerhard Zinser

 

19:30 - Reception at “Brenner’s Park Hotel”

 

20:00 - Gala dinner

 

 

 

Saturday, 21th September 2019

 

 

08:30 - 10:00 5th Session - Neurobiology of the outer retina II
Moderators:
Thomas Langmann (Cologne/D)
Anneke den Hollander (Nijmegen/NL)

 

36 L
Janet Sparrow (Boston/USA)
Is lipofuscin a relevant factor in the pathogenesis of AMD?

 

37 P
Thomas Ach, K. Bermond, J. A. Gambril, C. Wobbe, A. Berlin,
R. Heintzmann, K.R. Sloan, C.A. Curcio (Würzburg/D, Jena/D, Birmingham/USA)
Cellular and subcellular changes in the RPE: from normal aging to early signs of AMD

 

38 L
Deborah A. Ferrington (Minneapolis/USA)
Primary RPE cultures from donors with AMD

 

39 P
Stephanie C. Joachim, N. Wagner, M. Gammel, A. Greulich, S. Reinehr, J. Hurst, H.B. Dick, S. Schnichels (Bochum/D, Tübingen/D)
Novel porcine organ culture model for AMD research

 

40 L
Anneke den Hollander (Nijmegen/NL)
Understanding disease mechanisms in AMD: From serum biomarkers to an organ-on-a-chip model for AMD

 

41 L
John G. Flannery, M.H. Berry, A. Holt, A. Salari, J. Veit, M. Visel, J. Levitz, K. Aghi, B. Gaub, B. Sivyer, E. Isacoff
(California/USA, Oregon/USA, New York/USA, Zürich/CH)
Restoration of high-sensitivity and adapting vision with a cone opsin

 

42 L
Volker Busskamp (Bonn/D)
Programming human stem cells to cone photoreceptors

 

43 P
Giuliana Gagliardi, D.M. Feitosa-Afonsso, Y.B. Arik, J. Heesterbeek, C.B. Hoyng, A.D. van der Meer, A.I. den Hollander
(Nijmegen/NL, Enschede/NL)
Using human-induced pluripotent stem cells for modelling the blood-retinal-barrier on-a-chip

 

 

10:00 - 10:45 6th Session - Rapid Fire Presentations

 

 

11:15 - 13:00 7th Session - Phenotyping AMD: Advances in Imaging
Moderators:
Richard F. Spaide (New York/USA)
Giovanni Staurenghi (Milan/I)

 

44 L
SriniVas Sadda (Los Angeles/USA)
Choriocapillaris status as a risk factor in AMD

 

45 L
Philip J. Rosenfeld (Miami/USA)
Choriocapillaris imaging using SS-OCT angiography in AMD

 

46 P
Martin Hammer, R. Schultz, D. Meller (Jena/D)
Clinicopathologic comparison of fluorescence lifetimes and spectral characteristics in AMD

 

47 L
Sebastian Wolf, C. Dysli, M.S. Zinkernagel (Bern/CH)
Fluorescence lifetimes in AMD

 

48 P
Lydia Sauer, A.S. Vitale, N.K. Modersitzki, E.D. Hansen, C. B. Komanski, P.S. Bernstein (Salt Lake City/USA)
Imaging of AMD with FLIO

 

49 L
Adam Dubis (London/GB)
Adaptive optics photoreceptor imaging, function and survival in AMD

 

50 P
Thomas Theelen, P.P.A. Dhooge, T.W.F. Mulders, C.B. Hoyng (Nijmegen/NL)
In vivo photoreceptor imaging by non-adaptive optics confocal scanning laser ophthalmoscopy

 

51 P
R. Theodore Smith, K.B. Freund (New York City/USA)
Quantitative fundus autofluorescence (qAF) of GA secondary to AMD

 

52 L
Daniel F. Martin (Cleveland/USA)
Why did GA trials fail - how to overcome obstacles?

 

53 P
Victor Chong (Ingelheim/D)
Neuroprotection as a therapeutic option for GA

 

13:00 - 14:00 - Lunch

 

 

14:00 - 17:30 8th Session - Dissecting AMD: Novel approaches
Moderators:
Frank G. Holz (Bonn/D)
Daniel Pauleikhoff (Mpnster/D)

 

 

54 L
Adnan Tufail (London/GB)
Application of deep learning-based automated segmentation in OCT on AMD

 

55 L
Aaron Lee (Washington/USA)
Deep learning applications with OCT in AMD

 

56 L
Karl Csaky, M. Oulette, C. Clark (Dallas/USA, Plano/USA)
Developing human based intuitive deep learning
algorithms for analyzing intermediate AMD OCT-Images

 

57 L
Glenn J. Jaffe (Durham/GB)
Challenges of clinical relevant phenotyping of exudative AMD

 

58 L
Richard F. Spaide (New York/USA)
OCT-angiography – dissecting neovasular AMD

 

59 L
Giuseppe Querques, R. Sacconi, V. Capuano, A. Carnevali, D. Colantuono, M. Battista, E. Borrelli,
A. Miere, M.Parravano, E. Costanzo, L. Querques, E.H. Souied, F. Bandello
(Milan/Creteil/F, Catanzaro/I, Rome/I)
„Quiescent“ CNV in AMD – characteristics and consequences

 

60 P
Maximilian Pfau, L. von der Emde, C. Dysli, P.T. Möller, S. Thiele, M. Lindner, M. Schmid,
S. Schmitz-Valckenberg, F.G. Holz, M. Fleckenstein
(Bonn/D, Bern/CH, Oxford/GB)
Type-1 choroidal neovascularization reduces the progression of atrophy in eyes with AMD

 

61 L
David Sarraf (Los Angeles/USA)
Mechanisms and pathways of PED development in neovascular AMD

 

62 L
K. Bailey Freund (New York City/USA)
Type 3 CNV – a specific phenotype?

 

63 L
John Marshall (London/GB)
Can a nanosecond beam modulated laser improve transport mechanisms and delaying progression towards late AMD?

 

64 L
Robyn Guymer - LEAD study team (Melbourne/AUS)
Natural history and modulation of drusen by laser:
The LEAD randomized controlled trial of sub-threshold nanosecond laser intervention in AMD

 

65 L
Eric Souied (Paris/F)
Scarring of CNV – differentiation by multimodal imaging?

 

66 L
Daniel Pauleikhoff, M.L. Farecki, H. Faatz, K. Rothaus, G. Spital, A. Lommatzsch (Münster/D)
Mathematical characterization of CNV before and under anti-VEGF-therapy

 

67 L
Usha Chakravarthy, B. Reeves, R. Evans, C. Rogers (Belfast/GB, Bristol/GB)
Extended follow up from the IVAN trial

 

68 P
Heinrich Gerding (Olten/CH)
10 years anti-VEGF treatment outcomes on neovascular AMD

 

69 L
Ricarda G. Schumann, V. Deiters, S.R. Günther, D. Vogt, J. Siedlecki, S.G. Priglinger (Munich/D)
Long-term visual acuity outcomes and anatomic results from anti-VEGF-therapy in patients with neovascular AMD in a real-life setting

 

70 P
Jakob Siedlecki, C. Fischer, B. Schworm, T.C. Kreutzer, K. Kortüm, R. Schumann, A. Wolf, S.G. Priglinger (Munich/D)
Long-term incidence of macular atrophy and clinical outcomes in neovascular AMD managed to sub-retinal fluid only

 

17:30 Adjourn
Frank G. Holz
Daniel Pauleikhoff

Veranstaltungsort:
Kongresshaus Baden-Baden
Anschrift:
Augustaplatz 10
76530 Baden-Baden, Deutschland
Veranstalter:
Augenabteilung am St. Franziskus-Hospital Münster
Organisation:

Congress-Organisation Gerling GmbH
Werftstraße 23
DE - 40549 Düsseldorf
Tel.: +49 (0)211 592 244
Fax: +49 (0)211 593 560

Ausrichter: 

Prof. Dr. Daniel Pauleikhoff
St. Franziskus Hospital -Augenabteilung-
Hohenzollernring 74, 48145 Münster
Tel.: (+49) 02 51 / 93 52-7 11
Fax: (+49) 02 51 / 93 52-7 19

 
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Friday, September 20th 2019
at 19.30 Reception

 

20.00 Gala dinner
Orangerie at Brenner’s Parkhotel
Schillerstraße 4-6, Baden-Baden

 

Musical entertainment by the Tommy Wetzel Combo

 

Price per person (incl. dinner and drinks):
Regular € 65
Resident/Fellow/Student € 45